Raltegravir is for use in adults and children who weigh at least 4.4 pounds (2 kilograms).
Before taking this medicine
To make sure Isentress is safe for you, tell your doctor if you have ever had:
- a muscle disorder;
- kidney disease (or if you are on dialysis);
- liver disease; or
- mental illness or depression.
It is not known whether Isentress will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medicine.
If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of Isentress on the baby.
Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
What are the side effects of Isentress?
The most commonly reported side effects when taking Isentress tablets 400mg include: nausea, vomiting, headaches, tiredness, inflammation of the nasal passages and throat, trouble sleeping, upper respiratory tract infection, cough, fever, bronchitis, back pain and depression. A more serious but less common side effect is a condition is a severe skin reaction including Stevens-Johnson syndrome and toxic epidermal necrolysis.
When should Isentress not be used?
You should not use Isentress tablets 400mg if you:
- are allergic to raltegravir or any ingredients in Isentress
- are pregnant or are breastfeeding
- are taking medicines that interact with Isentress, including antacids containing aluminium and/or magnesium, the anti-infective rifampicin
You should take your Isentress tablets 400mg with a glass of water twice daily, with or without food and in combination with other antiretroviral drugs that have been prescribed. You should continue to take your Isentress tablets 400mg for as long as recommended by your doctor, and you will be monitored carefully to ensure that you do not develop any serious side effects, in which case your doctor will probably recommend that you stop taking your Isentress tablets 400mg.
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